Tandutinib hydrochloride (MLN518 hydrochloride) is a potent and selective inhibitor of the FLT3 with an IC50 of 0.22 µM, and also inhibits c-Kit and PDGFR with IC50s of 0.17 µM and 0.20 µM, respectively. Tandutinib hydrochloride can be used for acute myelogenous leukemia (AML)[1][2]. Tandutinib hydrochloride has the ability to cross the blood-brain barrier[3].
Molecular Weight:
599.16
Purity:
99.29
CAS Number:
[2438900-70-8]
Formula:
C31H43ClN6O4
Target:
Apoptosis,c-Kit,FLT3,PDGFR
Application Notes:
Reference compound
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