OSI-930 is an orally selective inhibitor of Kit, KDR and CSF-1R (c-Fms) with IC50s of 80 nM, 9 nM and 15 nM, respectively. OSI-930 also moderately inhibits Flt-1, c-Raf, Lck and low activity against PDGFRalpha/beta, Flt-3 and Abl. OSI-930 has antitumor activity[1].
Molecular Weight:
443.44
Purity:
99.01
CAS Number:
[728033-96-3]
Formula:
C22H16F3N3O2S
Target:
Apoptosis,c-Fms,c-Kit,VEGFR
Application Notes:
MCE Product type: Reference compound
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