KDOAM-25 is a potent and highly selective histone lysine demethylases 5 (KDM5) inhibitor with IC50s of 71 nM, 19 nM, 69 nM, 69 nM for KDM5A, KDM5B, KDM5C, KDM5D, respectively. KDOAM-25 increases global H3K4 methylation at transcriptional start sites and impairs proliferation in multiple myeloma MM1S cells[1].
Molecular Weight:
307.39
CAS Number:
[2230731-99-2]
Formula:
C15H25N5O2
Target:
Histone Demethylase
Application Notes:
MCE Product type: Reference compound
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