Cediranib (AZD2171) is a highly potent, orally available and blood-brain barrier permeability VEGFR tyrosine kinase inhibitor with IC50s of <1, <3, 5, 5, 36, 2 nM for Flt1, KDR, Flt4, PDGFRalpha, PDGFRbeta, c-Kit, respectively.
Molecular Weight:
450.51
Purity:
99.87
CAS Number:
[288383-20-0]
Formula:
C25H27FN4O3
Target:
Autophagy,PDGFR,VEGFR
Application Notes:
MCE Product type: Reference compound
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