DCEBIO is a small/medium conductance calcium-activated potassium (SKCa/IKCa) channel opener and primary neuron signal blocker. It hyperpolarizes the membrane potential of C2C12 myoblasts by activating IKCa channels, thereby promoting myogenic differentiation. The specific biological activity of DCEBIO is manifested in increased myotube formation, enhanced myosin heavy chain II protein levels and myogenin mRNA levels. DCEBIO can be applied in the field of muscle research, especially in muscle-related degenerative diseases such as sarcopenia[1][2][3].
Molecular Weight:
231.08
Purity:
99.25
CAS Number:
[60563-36-2]
Formula:
C9H8Cl2N2O
Target:
Potassium Channel
Application Notes:
MCE Product type: Reference compound
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