SR 57227A is a potent, orally active and selective 5-HT3 receptor agonist, with ability to cross the blood brain barrier. SR 57227A has affinities (IC50) varying between 2.8 and 250 nM for 5-HT3 receptor binding sites in rat cortical membranes and on whole NG 108-15 cells or their membranes. Anti-depressant effects[1][2].
Molecular Weight:
248.15
Purity:
99.76
CAS Number:
[77145-61-0]
Formula:
C10H15Cl2N3
Target:
5-HT Receptor
Application Notes:
Reference compound
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