NS13001 is a potent, selective, orally active allosteric positive modulator of SK channels (small conductance calcium-activated potassium channels). The EC50s are 1.8 and 0.14 µM for SK2 and SK3, respectively. NS13001 holds promise as a potential therapeutic agent for treatment of spinocerebellar ataxia type 2 (SCA2) and possibly other cerebellar ataxias[1].
Molecular Weight:
353.81
Purity:
99.62
CAS Number:
[1063331-94-1]
Formula:
C17H16ClN7
Target:
Potassium Channel
Application Notes:
MCE Product type: Reference compound
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