TG53 is a potent inhibitor of tissue transglutaminase (TG2) and fibronectin (FN) protein-protein interaction. TG53 inhibits formation of a complex with integrin beta1 and activation of FAK and c-Src during SKOV3 cell attachment onto FN. TG53 can be used for ovarian cancer research[1].
Molecular Weight:
411.88
CAS Number:
[946369-04-6]
Formula:
C21H22ClN5O2
Target:
FAK,Glutaminase,Integrin,Src
Application Notes:
MCE Product type: Reference compound
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