ZINC69391, a specific Rac1 inhibitor, interferes with Rac1-GEF interaction by masking Trp56 residue on Rac1 surface. ZINC69391 interferes with the interaction of Rac1 with Dock180 and reduces Rac1-GTP levels. ZINC69391 induces apoptosis, and shows antiproliferative and antimetastatic effects[1][2][3].
Molecular Weight:
309.29
Purity:
99.12
CAS Number:
[303094-67-9]
Formula:
C14H14F3N5
Target:
Apoptosis,Ras
Application Notes:
MCE Product type: Reference compound
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