Tanespimycin, CAS [[75747-14-7]]

Product Overview

• Article Name: Tanespimycin, CAS [[75747-14-7]]
• Biozol Catalog Number: MCE-HY-10211
• Supplier Catalog Number: HY-10211
• Alternative Catalog Number: MCE-HY-10211-5MG,MCE-HY-10211-200MG,MCE-HY-10211-10MG,MCE-HY-10211-25MG,MCE-HY-10211-50MG,MCE-HY-10211-10MMX1ML,MCE-HY-10211-100MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: 17-AAG, NSC 330507, CP 127374

Product Description

Tanespimycin (17-AAG) is a potent HSP90 inhibitor with an IC50 of 5 nM, having a 100-fold higher binding affinity for tumour cell derived HSP90 than normal cell derived HSP90[1][5]. Tanespimycin depletes cellular STK38/NDR1 and reduces STK38 kinase activity. Tanespimycin also downregulates the stk38 gene expression[3].

Product Properties

• Molecular Weight: 585.69
• Purity: 99.01
• CAS Number: [75747-14-7]
• Formula: C31H43N3O8
• Target: Antibiotic,Apoptosis,Autophagy,Bacterial,HSP,Mitophagy

Application Notes

• Application Notes: MCE Product type: Reference compound