Tanespimycin (Standard), CAS [[75747-14-7]]

Product Overview

• Article Name: Tanespimycin (Standard), CAS [[75747-14-7]]
• Biozol Catalog Number: MCE-HY-10211R
• Supplier Catalog Number: HY-10211R
• Alternative Catalog Number: MCE-HY-10211R-100MG,MCE-HY-10211R-5MG,MCE-HY-10211R-25MG,MCE-HY-10211R-10MG,MCE-HY-10211R-50MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: 17-AAG (Standard), NSC 330507 (Standard), CP 127374 (Standard)

Product Description

Tanespimycin (Standard) is the analytical standard of Tanespimycin. This product is intended for research and analytical applications. Tanespimycin (17-AAG) is a potent HSP90 inhibitor with an IC50 of 5 nM, having a 100-fold higher binding affinity for tumour cell derived HSP90 than normal cell derived HSP90[1][5]. Tanespimycin depletes cellular STK38/NDR1 and reduces STK38 kinase activity. Tanespimycin also downregulates the stk38 gene expression[3].

Product Properties

• Molecular Weight: 585.69
• Purity: 98.72
• CAS Number: [75747-14-7]
• Formula: C31H43N3O8
• Target: Antibiotic,Apoptosis,Autophagy,Bacterial,HSP,Mitophagy,Reference Standards

Application Notes

• Application Notes: MCE Product type: Reference Standards