BIIB021 (mesylate), CAS [[1225041-97-3]] Preis auf Anfrage

Product Overview

• Article Name: BIIB021 (mesylate), CAS [[1225041-97-3]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-10212A
• Supplier Catalog Number: HY-10212A
• Alternative Catalog Number: MCE-HY-10212A-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: CNF2024 (mesylate)

Product Description

BIIB021 (CNF2024) mesylate is the mesylate of BIIB021 (HY-10212). BIIB021 is an orally active Hsp90 inhibitor. BIIB021 inhibits the proliferation of chronic myeloid leukemia (CML) cells, with IC50 values of K562, K562/G, 32Dp210, and 32Dp210-T315I cells are 513.99, 603.53, 110.08, and 148.07 nM, respectively. BIIB021 degrades BCR-ABL protein and inhibits the beta-catenin/c-Myc pathway. BIIB021 can also induce autophagy in CML cells. BIIB021 can be used for the research of CML[1].

Product Properties

• Molecular Weight: 414.87
• CAS Number: [1225041-97-3]
• Formula: C15H19ClN6O4S
• Target: Autophagy,c-Myc,HSP,beta-catenin

Application Notes

• Application Notes: MCE Product type: Reference compound