SNX-2112, CAS [[908112-43-6]]

Product Overview

• Article Name: SNX-2112, CAS [[908112-43-6]]
• Biozol Catalog Number: MCE-HY-10214
• Supplier Catalog Number: HY-10214
• Alternative Catalog Number: MCE-HY-10214-10MMX1ML,MCE-HY-10214-5MG,MCE-HY-10214-10MG,MCE-HY-10214-100MG,MCE-HY-10214-50MG,MCE-HY-10214-25MG,MCE-HY-10214-200MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: PF-04928473

Product Description

SNX-2112 (PF 04928473) is an orally active Hsp90 inhibitor, with a Kd of 16 nM for Hsp90 and IC50s of 30 nM, 30 nM for Hsp90 alpha and Hsp90 beta, also induces Her-2 degradation, and inhibits Grp94 and Trap-1, with IC50s of 10 nM, 4.275 µM and 0.862 µM, respectively[1]. SNX-2112 (PF 04928473) binds Hsp90 isoforms Hsp90alpha, Hsp90beta and Hsp90b1/Grp94 with Kds of 4 nM, 6 nM and 484 nM, respectively[2].

Product Properties

• Molecular Weight: 464.48
• Purity: 99.49
• CAS Number: [908112-43-6]
• Formula: C23H27F3N4O3
• Target: Autophagy,HSP

Application Notes

• Application Notes: Reference compound