SNX-2112 (Standard), CAS [[908112-43-6]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-10214R
Supplier Catalog Number:
HY-10214R
Alternative Catalog Number:
MCE-HY-10214R-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
SNX-2112 (Standard) is the analytical standard of SNX-2112 (HY-10214). This product is intended for research and analytical applications. SNX-2112 (PF 04928473) is an orally active Hsp90 inhibitor, with a Kd of 16 nM for Hsp90 and IC50s of 30 nM, 30 nM for Hsp90 alpha and Hsp90 beta, also induces Her-2 degradation, and inhibits Grp94 and Trap-1, with IC50s of 10 nM, 4.275 µM and 0.862 µM, respectively[1]. SNX-2112 (PF 04928473) binds Hsp90 isoforms Hsp90alpha, Hsp90beta and Hsp90b1/Grp94 with Kds of 4 nM, 6 nM and 484 nM, respectively[2].
Molecular Weight:
464.48
CAS Number:
[908112-43-6]
Formula:
C23H27F3N4O3
Target:
Autophagy,HSP,Reference Standards
Application Notes:
MCE Product type: Reference Standards
* VAT and and shipping costs not included. Errors and price changes excepted
