Everolimus (RAD001) is a Rapamycin (HY-10219) derivative and a potent, selective and orally active mTOR1 inhibitor. Everolimus binds to FKBP-12 to generate an immunosuppressive complex. Everolimus inhibits tumor cells proliferation and induces cell apoptosis and autophagy. Everolimus has potent immunosuppressive and anticancer activities[1][2].
Molecular Weight:
958.22
Purity:
99.85
CAS Number:
[159351-69-6]
Formula:
C53H83NO14
Target:
Apoptosis,Autophagy,Bacterial,FKBP,mTOR
Application Notes:
Reference compound
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