JNJ-16241199, CAS [[604769-01-9]]

Product Overview

• Article Name: JNJ-16241199, CAS [[604769-01-9]]
• Biozol Catalog Number: MCE-HY-10226
• Supplier Catalog Number: HY-10226
• Alternative Catalog Number: MCE-HY-10226-5MG,MCE-HY-10226-10MMX1ML,MCE-HY-10226-1MG,MCE-HY-10226-10MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: R306465

Product Description

JNJ-16241199 (R306465) is an orally active, selectivehydroxamate-based histone deacetylase (HDAC) inhibitor, with theIC50of 3.3 nM and 23 nM for HDAC1and HDAC8, respectively.JNJ-16241199induces histone 3 acetylation and strongly increases the expression of p21waf1, cip1 in A2780 ovarian carcinoma cells.JNJ-16241199 inducescell apoptosisand shows anticancer activityin a broad spectrum of human malignancies. JNJ-16241199 can be used for cancer study[1].

Product Properties

• Molecular Weight: 413.45
• Purity: 99.05
• CAS Number: [604769-01-9]
• Formula: C19H19N5O4S
• Target: Apoptosis,HDAC

Application Notes

• Application Notes: Reference compound