Motesanib (AMG 706) is a potent ATP-competitive inhibitor of VEGFR1/2/3 with IC50s of 2 nM/3 nM/6 nM, respectively, and has similar activity against Kit, and is appr 10-fold more selective for VEGFR than PDGFR and Ret.
Molecular Weight:
373.45
Purity:
99.96
CAS Number:
[453562-69-1]
Formula:
C22H23N5O
Target:
c-Kit,VEGFR
Application Notes:
Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted