Motesanib (Standard) is the analytical standard of Motesanib. This product is intended for research and analytical applications. Motesanib (AMG 706) is a potent ATP-competitive inhibitor of?VEGFR1/2/3?with?IC50s?of 2 nM/3 nM/6 nM, respectively, and has similar activity against Kit, and is appr 10-fold more selective for VEGFR than PDGFR and Ret.
Molecular Weight:
373.45
CAS Number:
[453562-69-1]
Formula:
C22H23N5O
Target:
c-Kit,Reference Standards,VEGFR
Application Notes:
MCE Product type: Reference Standards
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