Motesanib Diphosphate (AMG 706 Diphosphate) is a potent ATP-competitive inhibitor of VEGFR1/2/3 with IC50s of 2 nM/3 nM/6 nM, respectively, and has similar activity against Kit, and is approximately 10-fold more selective for VEGFR than PDGFR and Ret.
Molecular Weight:
569.44
Purity:
99.86
CAS Number:
[857876-30-3]
Formula:
C22H29N5O9P2
Target:
c-Kit,VEGFR
Application Notes:
Reference compound
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