THIP (Gaboxadol) is a selective extrasynaptic GABAA receptors (eGABARs) agonist (with blood-brain barrier permeability), shows an EC50 value of 13 µM for delta-GABAAR. THIP induces strong tense GABAA-mediated currents in layer 2/3 neurons, but shows on effect on miniature IPSCs. THIP can be used in studies of sleep disorders[1][2][3].
Molecular Weight:
140.14
Purity:
99.93
CAS Number:
[64603-91-4]
Formula:
C6H8N2O2
Target:
GABA Receptor
Application Notes:
MCE Product type: Reference compound1
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