Simeprevir (sodium), CAS [[1241946-89-3]] Preis auf Anfrage

Product Overview

• Article Name: Simeprevir (sodium), CAS [[1241946-89-3]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-10241A
• Supplier Catalog Number: HY-10241A
• Alternative Catalog Number: MCE-HY-10241A-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: TMC435 (sodium), TMC435350 (sodium)

Product Description

Simeprevir (TMC435, TMC435350) sodium is an oral, potent and highly specific hepatitis C virus (HCV) NS3/4A protease inhibitor with a Ki of 0.36 nM. Simeprevir sodium inhibits HCV replication with an EC50 of 7.8 nM. Simeprevir sodium also potently suppresses SARS-CoV-2 replication and synergizes with Remdesivir. Simeprevir sodium inhibits the main protease (Mpro) and the RNA-dependent RNA polymerase (RdRp) of SARS-CoV-2, and also modulates host immune responses[1][4].

Product Properties

• CAS Number: [1241946-89-3]
• Formula: C38H47N5O7S2.xNa
• Target: DNA/RNA Synthesis,HCV,HCV Protease,SARS-CoV

Application Notes

• Application Notes: Reference compound