NVP-ADW742 (ADW742) is an orally active, selective IGF-1R tyrosine kinase inhibitor with an IC50 of 0.17 µM. NVP-ADW742 inhibits insulin receptor (InsR) with an IC50 of 2.8 µM. NVP-ADW742 induces pleiotropic antiproliferative/proapoptotic biologic sequelae in tumor cells[1][2].
Molecular Weight:
453.58
Purity:
99.30
CAS Number:
[475488-23-4]
Formula:
C28H31N5O
Target:
Apoptosis,IGF-1R,Insulin Receptor
Application Notes:
MCE Product type: Reference compound
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