Sunitinib-d10 (SU 11248-d10) is a deuterium labeled Sunitinib. Sunitinib is a multi-targeted receptor tyrosine kinase inhibitor with IC50s of 80 nM and 2 nM for VEGFR2 and PDGFRbeta, respectively[1]. Sunitinib, an ATP-competitive inhibitor, effectively inhibits autophosphorylation of Ire1alpha by inhibiting autophosphorylation and consequent RNase activation[2].
Molecular Weight:
408.54
Purity:
99.89
CAS Number:
[1126721-82-1]
Formula:
C22H17D10FN4O2
Target:
Apoptosis,Autophagy,IRE1,Mitophagy,PDGFR,VEGFR
Application Notes:
MCE Product type: Isotope-Labeled Compounds
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