Sunitinib-d4, CAS [[1126721-79-6]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-10255AS1
Supplier Catalog Number:
HY-10255AS1
Alternative Catalog Number:
MCE-HY-10255AS1-1MG
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Sunitinib-d4 is the deuterium labeled Sunitinib. Sunitinib (SU 11248) is a multi-targeted receptor tyrosine kinase inhibitor with IC50s of 80 nM and 2 nM for VEGFR2 and PDGFRbeta, respectively[1]. Sunitinib, an ATP-competitive inhibitor, effectively inhibits autophosphorylation of Ire1alpha by inhibiting autophosphorylation and consequent RNase activation[2].