Vandetanib (D6474) is a potent, orally active inhibitor of VEGFR2/KDR tyrosine kinase activity (IC50=40 nM). Vandetanib also has activity versus the tyrosine kinase activity of VEGFR3/FLT4 (IC50=110 nM) and EGFR/HER1 (IC50=500 nM)[1].
Molecular Weight:
475.35
Purity:
99.95
CAS Number:
[443913-73-3]
Formula:
C22H24BrFN4O2
Target:
Apoptosis,Autophagy,VEGFR
Application Notes:
MCE Product type: Reference compound
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