Afatinib (dimaleate), CAS [[850140-73-7]]

Product Overview

• Article Name: Afatinib (dimaleate), CAS [[850140-73-7]]
• Biozol Catalog Number: MCE-HY-10261A
• Supplier Catalog Number: HY-10261A
• Alternative Catalog Number: MCE-HY-10261A-5MG,MCE-HY-10261A-50MG,MCE-HY-10261A-25MG,MCE-HY-10261A-10MG,MCE-HY-10261A-500MG,MCE-HY-10261A-200MG,MCE-HY-10261A-1G,MCE-HY-10261A-100MG,MCE-HY-10261A-10MMX1ML
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: BIBW 2992MA2

Product Description

Afatinib (BIBW 2992) dimaleate is an orally active, potent and irreversible dual specificity inhibitor of ErbB family (EGFR and HER2), with IC50 values of 0.5 nM, 0.4 nM, 10 nM and 14 nM for EGFRwt, EGFRL858R, EGFRL858R/T790M and HER2, respectively. Afatinib dimaleate can be used for the research of esophageal squamous cell carcinoma (ESCC), non-small cell lung cancer (NSCLC) and gastric cancer[1][2][3][4].

Product Properties

• Molecular Weight: 718.08
• Purity: 99.74
• CAS Number: [850140-73-7]
• Formula: C32H33ClFN5O11
• Target: Akt,Apoptosis,Autophagy,c-Met/HGFR,EGFR,p38 MAPK

Application Notes

• Application Notes: MCE Product type: Reference compound