Afatinib-d6 (dimaleate) is the deuterium labeled Afatinib dimaleate. Afatinib dimaleate is an irreversible EGFR family inhibitor with IC50s of 0.5 nM, 0.4 nM, 10 nM and 14 nM for EGFRwt, EGFRL858R, EGFRL858R/T790M and HER2, respectively[1][2].
Molecular Weight:
724.12
Formula:
C32H27D6ClFN5O11
Target:
Autophagy,EGFR,Isotope-Labeled Compounds
Application Notes:
MCE Product type: Isotope-Labeled Compounds
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