Afatinib (oxalate), CAS [[1398312-64-5]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-10261D
Supplier Catalog Number:
HY-10261D
Alternative Catalog Number:
MCE-HY-10261D-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Alternative Names:
BIBW 2992 (oxalate)
Afatinib (BIBW 2992) oxalate is an orally active, potent and irreversible dual specificity inhibitor of ErbB family (EGFR and HER2), with IC50 values of 0.5 nM, 0.4 nM, 10 nM and 14 nM for EGFRwt, EGFRL858R, EGFRL858R/T790M and HER2, respectively. Afatinib oxalate can be used for the research of esophageal squamous cell carcinoma (ESCC), non-small cell lung cancer (NSCLC) and gastric cancer[1][2][3][4].
Molecular Weight:
575.97
CAS Number:
[1398312-64-5]
Formula:
C26H27ClFN5O7
Target:
Akt,Apoptosis,Autophagy,c-Met/HGFR,EGFR
Application Notes:
MCE Product type: Reference compound
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