(R)-Afatinib, CAS [[439081-17-1]] Preis auf Anfrage

Product Overview

• Article Name: (R)-Afatinib, CAS [[439081-17-1]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-10261E
• Supplier Catalog Number: HY-10261E
• Alternative Catalog Number: MCE-HY-10261E-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: (R)-BIBW 2992

Product Description

(R)-Afatinib ((R)-BIBW 2992) is the Afatinib isomer. Afatinib (HY-10261) is an orally active, potent and irreversible dual specificity inhibitor of?ErbB?family (EGFR?and?HER2), with?IC50?values of 0.5 nM, 0.4 nM, 10 nM and 14 nM for?EGFRwt, EGFRL858R,?EGFRL858R/T790M?and HER2, respectively. Afatinib can be used for the research of esophageal squamous cell carcinoma (ESCC), non-small cell lung?cancer?(NSCLC) and gastric?cancer[1].

Product Properties

• Molecular Weight: 485.94
• CAS Number: [439081-17-1]
• Formula: C24H25ClFN5O3
• Target: c-Met/HGFR,EGFR,p38 MAPK

Application Notes

• Application Notes: MCE Product type: Reference compound