Afatinib-d4 is the deuterium labeled Afatinib. Afatinib (BIBW 2992) is an irreversible EGFR family inhibitor with IC50s of 0.5 nM, 0.4 nM, 10 nM and 14 nM for EGFRwt, EGFRL858R, EGFRL858R/T790M and HER2, respectively.
Molecular Weight:
489.96
Formula:
C24H21D4ClFN5O3
Target:
Autophagy,EGFR
Application Notes:
MCE Product type: Isotope-Labeled Compounds
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