()-Enitociclib (Standard), CAS [[1610358-53-6]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-103019AR
Supplier Catalog Number:
HY-103019AR
Alternative Catalog Number:
MCE-HY-103019AR-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
()-Enitociclib (Standard) is the analytical standard of ()-Enitociclib (HY-103019A). This product is intended for research and analytical applications. ()-Enitociclib (()-BAY-1251152) is the racemic mixture of Enitociclib (HY-103019E). Enitociclib is a selective CDK9 inhibitor and apoptosis inducer. Enitociclib inhibits CDK9 activity and reduces the phosphorylation of Ser2 in the carboxyl-terminal domain (CTD) of RNA polymerase Pol II, thereby downregulating the transcription of key oncogenes such as MYC and MCL1. Enitociclib has anti-proliferative activity targeting MYC+ lymphoma and multiple myeloma (MM) cells, and has synergistic effects with Bortezomib (HY-10227) and Lenalidomide (HY-A0003), and can be used in the research of hematological malignancies[1][2].
