Doramapimod (GMP), CAS [[285983-48-4]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-10320G
Supplier Catalog Number:
HY-10320G
Alternative Catalog Number:
MCE-HY-10320G-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Alternative Names:
BIRB 796 (GMP)
Doramapimod GMP (BIRB 796 GMP) is an orally active inhibitor for p38 MAPK, with IC50s of 38, 65, 200 and 520 nM, for p38alpha, p38beta, p38gamma, p38delta. Doramapimod exhibits cytotoxicity and antitumor activity against multiple myeloma, synergizes with multidrug resistance protein 1 (ABCB1) and aurora kinase inhibitor VX680, promoting their antitumor efficacy against oral epidermoid carcinoma and cervical cancer. Doramapimod also exhibits anti-inflammatory activity[1].
Molecular Weight:
527.66
CAS Number:
[285983-48-4]
Formula:
C31H37N5O3
Target:
p38 MAPK
Application Notes:
MCE Product type: GMP Small Molecules
* VAT and and shipping costs not included. Errors and price changes excepted
