Doramapimod (Standard) is the analytical standard of Doramapimod. This product is intended for research and analytical applications. Doramapimod (BIRB 796) is an orally active, highly potent p38 MAPK inhibitor, which has an IC50 for p38alpha=38 nM, for p38beta=65 nM, for p38gamma=200 nM, and for p38delta=520 nM. Doramapimod has picomolar affinity for p38 kinase (Kd=0.1 nM). Doramapimod also inhibits B-Raf with an IC50 of 83 nM[1][2].
Molecular Weight:
527.66
CAS Number:
[285983-48-4]
Formula:
C31H37N5O3
Target:
Autophagy,p38 MAPK,Raf,Reference Standards
Application Notes:
MCE Product type: Reference Standards
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