CHM-1, a microtubule-destabilizing agent, inhibits tubulin polymerization. CHM-1 is a potent and selective antimitotic antitumor activity against human hepatocellular carcinoma. CHM-1 induces growth inhibition and apoptosis via G2-M phase arrest in human hepatocellular carcinoma cells by activation of Cdc2 kinase activity[1][2][3].
Molecular Weight:
283.25
Purity:
99.57
CAS Number:
[154554-41-3]
Formula:
C16H10FNO3
Target:
Microtubule/Tubulin
Application Notes:
MCE Product type: Reference compound
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