CL-387785 (Standard), CAS [[194423-06-8]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-10325R
Supplier Catalog Number:
HY-10325R
Alternative Catalog Number:
MCE-HY-10325R-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Alternative Names:
EKI-785 (Standard), WAY-EKI 785 (Standard)
CL-387785 (EKI-785, WAY-EKI 785) (Standard) is the analytical standard of CL-387785 (HY-10325). This product is intended for research and analytical applications. CL-387785 is an orally active EGFR inhibitor with an IC50 of 370 pM. CL-387785 inhibits EGF-stimulated EGFR autophosphorylation with an IC50 of approximately 5 nM. CL-387,785 exerts selective inhibition on cell lines overexpressing EGFR or c-erbB-2, whereas it shows weak inhibitory effects on cell lines with low expression of these two receptors. CL-387785 effectively induces cell cycle arrest and apoptosis. CL-387785 can be used for the research of non-small cell lung cancer and autosomal recessive polycystic kidney disease.
Molecular Weight:
381.23
CAS Number:
[194423-06-8]
Formula:
C18H13BrN4O
Target:
Apoptosis,EGFR,Reference Standards
Application Notes:
MCE Product type: Reference Standards
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