Neflamapimod (VX-745) is a potent, blood-brain barrier penetrant, highly selective inhibitor of p38alpha inhibitor with an IC50 for p38alpha of 10 nM and for p38beta of 220 nM. Neflamapimod (VX-745) possesses anti-inflammatory activity.
Molecular Weight:
436.26
Purity:
99.32
CAS Number:
[209410-46-8]
Formula:
C19H9Cl2F2N3OS
Target:
Autophagy,p38 MAPK
Application Notes:
MCE Product type: Reference compound
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