Toceranib phosphate (SU11654 phosphate) is an orally active receptor tyrosine kinase (RTK) inhibitor, and it potently inhibits PDGFR, VEGFR, and Kit with Kis of 5 and 6 nM for PDGFRbeta and Flk-1/KDR, respectively. Toceranib phosphate (SU11654 phosphate) has antitumor and antiangiogenic activity, and used in the treatment of canine mast cell tumors[1] [2].
Molecular Weight:
494.45
Purity:
99.23
CAS Number:
[874819-74-6]
Formula:
C22H28FN4O6P
Target:
c-Kit,PDGFR,VEGFR
Application Notes:
MCE Product type: Reference compound
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