Toceranib-d8 is the deuterium labeled Toceranib. Toceranib (SU11654) is an orally active receptor tyrosine kinase (RTK) inhibitor, and it potently inhibits PDGFR, VEGFR, and Kit with Kis of 5 and 6 nM for PDGFRbeta and Flk-1/KDR, respectively. Toceranib (SU11654) has antitumor and antiangiogenic activity, and used in the treatment of canine mast cell tumors[1][2].
Molecular Weight:
404.51
Purity:
99.08
CAS Number:
[1795134-78-9]
Formula:
C22H17D8FN4O2
Target:
c-Kit,Isotope-Labeled Compounds,PDGFR,VEGFR
Application Notes:
MCE Product type: Isotope-Labeled Compounds
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