Calhex 231 hydrochloride is a potent negative allosteric modulator that blocks (IC50 = 0.39 µM) increases in [3H]inositol phosphates elicited by activating the human wild-type CaSR transiently Ca2+-sensing receptor. Calhex 231 hydrochloride can be used in the study of traumatic hemorrhagic shock (THS) and diabetic cardiomyopathy (DCM)[1].
Molecular Weight:
443.41
Purity:
99.81
CAS Number:
[2387505-78-2]
Formula:
C25H28Cl2N2O
Target:
CaSR
Application Notes:
MCE Product type: Reference compound
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