L-006235 (Standard) is the analytical standard of L-006235. This product is intended for research and analytical applications. L-006235 (L-235) is a potent, selective, reversible and orally active inhibitor of cathepsin K, with an IC50 of 5 nM in bone resorption assay. L-006235 shows selectivity for cathepsin K (Ki=0.2 nM) over cathepsin B, cathepsin L, and cathepsin S (Ki=1, 6, and 47 µM, respectively). L-006235 can reduce collagen degradation and prevent bone loss[1][2].
Molecular Weight:
466.60
CAS Number:
[294623-49-7]
Formula:
C24H30N6O2S
Target:
Cathepsin,Reference Standards
Application Notes:
MCE Product type: Reference Standards
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