NSC693868 is a selective inhibitor of CDK1 and CDK5 with IC50s of 600 nM and 400 nM, respectively. NSC693868 less potently inhibits GSK3beta with an IC50 of 1 µM) and does not block CDC25 activity. NSC693868 is used to help define the roles of CDK1 and CDK5 in various signaling pathways[1].
Molecular Weight:
185.19
Purity:
99
CAS Number:
[40254-90-8]
Formula:
C9H7N5
Target:
CDK,GSK-3
Application Notes:
MCE Product type: Reference compound1
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