(R)-DRF053 dihydrochloride is a potent casein kinases 1 (CK1), CDK1/cyclin B and CDK5/p25 inhibitor with IC50s of 14 nM, 220 nM and 80 nM, respectively. (R)-DRF053 dihydrochloride prevents the CK1-dependent production of amyloid-beta in a cell model[1].
Molecular Weight:
490.43
Purity:
99.30
CAS Number:
[1241675-76-2]
Formula:
C23H29Cl2N7O
Target:
Casein Kinase,CDK
Application Notes:
MCE Product type: Reference compound1
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