Trimetrexate glucuronate (NSC 352122) is a folic acid antagonist. Trimetrexate glucuronate affects DNA and RNA synthesis by inhibiting dihydrofolate reductase and preventing the synthesis of purine nucleotides and thymidylate. Trimetrexate glucuronate has potential antitumour activity and can also be used to inhibit Pneumocystis carinii pneumonia[1][2].
Molecular Weight:
563.56
Purity:
98.09
CAS Number:
[82952-64-5]
Formula:
C25H33N5O10
Target:
Antifolate,Bacterial
Application Notes:
MCE Product type: Reference compound
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