Fasudil (HA-1077, AT877) is a nonspecific RhoA/ROCK inhibitor and also has inhibitory effect on protein kinases, with an Ki of 0.33 µM for ROCK1, IC50s of 0.158 µM and 4.58 µM, 12.30 µM, 1.650 µM for ROCK2 and PKA, PKC, PKG, respectively. Fasudil is also a potent Ca2+ channel antagonist and vasodilator[1][2][3].
Molecular Weight:
291.37
Purity:
99.91
CAS Number:
[103745-39-7]
Formula:
C14H17N3O2S
Target:
Autophagy,Calcium Channel,PKA,PKC,ROCK
Application Notes:
MCE Product type: Reference compound
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