Fasudil (dihydrochloride), CAS [[203911-27-7]]

Product Overview

• Article Name: Fasudil (dihydrochloride), CAS [[203911-27-7]]
• Biozol Catalog Number: MCE-HY-10341C
• Supplier Catalog Number: HY-10341C
• Alternative Catalog Number: MCE-HY-10341C-50MG,MCE-HY-10341C-25MG,MCE-HY-10341C-100MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: HA-1077 (dihydrochloride), AT-877 (dihydrochloride)

Product Description

Fasudil (HA-1077, AT877) dihydrochloride is a nonspecific RhoA/ROCK inhibitor and also has inhibitory effect on protein kinases, with an Ki of 0.33 µM for ROCK1, IC50s of 0.158 µM and 4.58 µM, 12.30 µM, 1.650 µM for ROCK2 and PKA, PKC, PKG, respectively. Fasudil dihydrochloride is also a potent Ca2+ channel antagonist and vasodilator[1][2][3].

Product Properties

• Molecular Weight: 364.29
• Purity: 99.98
• CAS Number: [203911-27-7]
• Formula: C14H19Cl2N3O2S
• Target: Autophagy,Calcium Channel,HIV,PKA,PKC,ROCK

Application Notes

• Application Notes: MCE Product type: Reference compound