A-841720 is a potent, non-competitive and selective mGlu1 receptor antagonist with an IC50 of 10 nM for human mGlu1 receptor. A-841720 displays 34-fold selectivity over mGlu5 (IC50 of 342 nM), and no significant activity at a range of other neurotransmitter receptors, ion channels, and transporters. A-841720 has the potential for chronic pain research[1][2].
Molecular Weight:
343.45
Purity:
98
CAS Number:
[869802-58-4]
Formula:
C17H21N5OS
Target:
mGluR
Application Notes:
MCE Product type: Reference compound
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