PROTAC Sirt2 Degrader-1 is a SirReal-based PROTAC, acts as a Sirt2 degrader, composed of a highly potent and isotype-selective Sirt2 inhibitor, a linker, and a bona fide Cereblon ligand for E3 ubiquitin ligase. PROTAC Sirt2 Degrader-1 shows an IC50 of 0.25 µM for Sirt2, with no effect on Sirt1/Sirt3 (IC50s>100 µM)[1].
Molecular Weight:
852.94
Purity:
98.71
CAS Number:
[2098487-75-1]
Formula:
C40H40N10O8S2
Target:
PROTACs,Sirtuin
Application Notes:
MCE Product type: Reference compound
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