Estramustine is an antineoplastic agent. Estramustine depolymerizes microtnbules by binding to tubulin 1, exhibits antimitotic activity with an IC50 value of ~16 µM for mitosis of DU 145 cells. Estramustine blocks cells at mitosis in prostate tumor xenografts[1].
Molecular Weight:
440.40
Purity:
99.15
CAS Number:
[2998-57-4]
Formula:
C23H31Cl2NO3
Target:
Microtubule/Tubulin,Mitosis
Application Notes:
MCE Product type: Reference compound
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