MKC8866 (Standard), CAS [[1338934-59-0]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-104040R
Supplier Catalog Number:
HY-104040R
Alternative Catalog Number:
MCE-HY-104040R-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
MKC8866 (Standard) is the analytical standard of MKC8866 (HY-104040). This product is intended for research and analytical applications. MKC8866, a salicylaldehyde analog, is a potent, selective IRE1 RNase inhibitor with an IC50 of 0.29 µM in human vitro. MKC8866 strongly inhibits Dithiothreitol-induced X-box-binding protein 1-spliced (XBP1s) expression with an EC50 of 0.52 µM and unstresses RPMI 8226 cells with an IC50 of 0.14 µM[1]. MKC8866 inhibits IRE1 RNase in breast cancer cells leading to the decreased production of pro-tumorigenic factors and it can inhibits prostate cancer (PCa) tumor growth[2].
Molecular Weight:
361.35
CAS Number:
[1338934-59-0]
Formula:
C18H19NO7
Target:
IRE1,Reference Standards
Application Notes:
MCE Product type: Reference Standards
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