Talmapimod (Standard), CAS [[309913-83-5]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-10406R
Supplier Catalog Number:
HY-10406R
Alternative Catalog Number:
MCE-HY-10406R-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Talmapimod (Standard) is the analytical standard of Talmapimod (HY-10406). This product is intended for research and analytical applications. Talmapimod (SCIO-469) is an orally active and selective inhibitor of p38alpha MAPK with an IC50 of 9 nM. Talmapimod inhibits the secretion of inflammatory factors (such as TNFalpha, IL-1beta, IL-6, and VEGF) by suppressing the p38alpha MAPK pathway, and it also inhibits angiogenesis and osteoclast activation. Talmapimod inhibits the growth of multiple myeloma cells and induces apoptosis. Talmapimod can be used to study various hematological malignancies (such as multiple myeloma, myelodysplastic syndrome)[1][2][3][4].
